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Latest update : 28 July 2014.

Scientific program

DAY 1: Sunday September 7th

16.00-17.30 Registration

17.30-17.50 Welcome address: Eric Reiter (Nouzilly, France)

17.50-17.55 Nicolas Fazzalari (Le Studium, Orléans, France)

18.00-19.00 Plenary lecture 1: W F Crowley Jr (Boston, USA)
The Unfolding Genetic Architecture of CNS Control of Human Reproduction

19.00- 21.00 Get-together-party

DAY 2: Monday September 8th

Session I: Regulation of gona dotropin secretion and action
Session chair : Ilpo Huhtaniemi (London, UK)

09.00-09.30 Daniel J. Bernard (Montreal, Canada): Regulation of FSH synthesis by members of the transforming growth factor β superfamily

09.30-10.00 Pam Mellon (San Diego, USA): Regulation of gonadotropin synthesis

10.00-10.30 Takashi Minegishi (Maebashi, Japan): Modulation of LHCGR action

10.30-11.30 Break/poster

11.30-12.00 Maris Laan (Tartu, Estonia): Genetics of gonadotropin action

12.00-12.30 Three short talks selected from posters

• Poster #10 Aleksandra Głodek
Methylation changes in human chorionic gonadotropin beta subunit genes promoter determines hCGβ expression in placenta

• Poster #13 Kim Jonas
Single molecule analysis of functionally asymetric GPCR oligomers reveals diverse spatial and structural signatures

• Poster #17 Jérôme Lannes
The role of miRNA132/212 in the regulation of mouse Follicle-Stimulating Hormone synthesis by gonadotropin-releasing hormone

12.30-14.30 Lunch/poster

DAY 2: Monday September 8th (continuing)

Session II: Clinical and translational aspects of gonadotropin action
Session chair : Alfredo Ulloa-Aguirre (Mexico City, Mexico)

14.30-15.00 Ana Claudia Zenclussen (Magdeburg, Germany): hCG and pregnancy immune tolerance

15.00-15.30 Waljit S. Dhillo (London, UK): Prospects of clinical application of kisspeptins

15.30-16.00 Selva Nataraja (TocopheRx, USA): Development of an orally active modulator of FSHR for infertility treatment

16.00-16.30 Break

16.30-17.00 Three short talks selected from posters

• Poster #4 Alexander Busch
FSHB -211G>T stratification for FSH treatment of male infertile patients

• Poster #6 Livio Casarini
β-arrestins regulate human FSHR signalling towards proliferative or apoptotic signals in granulosa cells in vitro

• Poster #19 Stella Campo
Gene expression profile of granulosa cells modulated by human FSH : role of oligosaccharide structure

17.00-17.15 Chris Van Koppen (Germany): Signaling of an allosteric, nanomolar potent, low molecular weight agonist for the follicle-stimulating hormone receptor

17.15-17.30 Richard Peck (Finox Biotech, Switzerland): FSH Biosimilars

17.30-18.00 Round table discussion: The future of gonadotropin therapeutics in ART with: Alfredo Ulloa-Aguirre (Moderator), Brian Arey (Bristol-Myers Squibb, USA), Chris Van Koppen (Germany), Richard Peck (Finox Biotech, Switzerland), Selva Nataraja (TocopheRx, USA)

18.00-19.00 Plenary lecture 2: Ilpo Huhtaniemi (London, UK): Function and dysfunction of the pituitary-gonadal axis

DAY 3: Tuesday September 9th

Session III: Structure/function sponsored by EMD Serono
Session chair: Yves Combarnous (Nouzilly, France)

09.00-09.30 Xuliang Jiang (EMD Serono, USA): Evidence for follicle-stimulating hormone receptor as a functional trimer

09.30-10.00 Gerd Krause (Berlin, Germany): GPCR crystal structures, relevance to gonadotropin receptor function

10.00-10.30 Jörg Gromoll (Muenster, Germany): Structural and functional plasticity of the LHCGR

10.30-11.30 Break/Poster

11.30-12.00 George Bousfield (Wichita, USA): FSH glycoforms

12.00-12.30 Manuela Simoni (Modena, Italy): Mutations and polymorphisms in FSH receptor implications in Human reproduction

12.30-14.30 Lunch/Posters

Session IV: Systems biology & signaling of gonadotropins
Session chair: James Dias (Albany, USA)

14.30-15.00 Peter Stanton (Clayton, Australia): MicroRNAs and gonadotropin action

15.00-15.30 Aylin Hanyaloglu (London, UK): Spatial programming of gonadotropin receptor signaling via membrane trafficking

15.30-16.00 Anne Poupon (Nouzilly, France): Systems biology approach to gonadotropin signaling

16.00-16.30 Break

16.30-17.00 Jerry Menon (Ann Arbor, USA): Novel pathways of gonadotropin signaling

17.00-17.30 T. Rajendra Kumar (Kansas City, USA): Gonadotropin re-routing and ovarian gene networks

17.30-18.30 Plenary lecture 3: Ursula Kaiser (Boston, USA): Gonadotropin Regulation: GnRH Pulse Frequency Decoding

20.30 – 23.00 Gala dinner at the City Hall

DAY 4: Wednesday September 10th

Session V: New ligands and actions of gonadotropin receptors
Session chair: George Bousfield (Wichita, KS, USA)

09.00-09.30 Eric Reiter (Nouzilly, France): β-arrestin-biased agonism at the FSH receptor

09.30-10.00 James Dias (Albany, USA): Negative allosteric modulators at the FSH receptor

10.00-10.30 Rajan Dighe (Bengalore, India): Antibodies as tools to understand receptor activation

10.30-11.00 Break

11.00-11.30 Elodie Kara (ReproPharm, France): Modulation of gonadotropins with potentiating antibodies

11.30-12.00 Manuel Tena-Sempere (Cordoba, Spain): Gonadotropin-inhibitory hormone

12.00-12.30 Concluding remarks: Alfredo Ulloa-Aguirre (Mexico City, Mexico).

12.30 Lunch

14.00 End of meeting

Articles in this section

  • 17 December 2013, by JOEL

International Conference on Gonadotropins & Receptors | Contact E-mail : eric.reiter@tours.inra.fr

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